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Antihistamines and codeine are both contraindicated to be used from the remedy of decrease respiratory tract symptoms, which include bronchial asthma.
Promethazine hydrochloride happens like a white to faint yellow, virtually odorless, crystalline powder which bit by bit oxidizes and turns blue on extended publicity to air.
Explain to your health care provider if your cough does not recover in 5 days. Also, inform your doctor Should your situation will get even worse, or Should you have a headache that does not go away, fever, or rash. These might be indicators of a serious healthcare trouble and will be checked by a health care provider.
For instance, numerous documented scenarios of Loss of life transpired during the put up-operative period of time adhering to tonsillectomy and/or adenoidectomy, and plenty of of the youngsters had proof of staying extremely-rapid metabolizers of codeine. Additionally, small children with obstructive slumber apnea who're handled with codeine for submit-tonsillectomy and/or adenoidectomy agony could possibly be notably sensitive to its respiratory depressant influence. Due to the risk of lifetime-threatening respiratory depression and Loss of life:
This product may perhaps include inactive ingredients, which may result in allergic reactions or other challenges. Talk with your pharmacist for more aspects.
Even though the threat of dependancy in any individual is not known, it could come about in people properly prescribed Promethazine HCl and Codeine Phosphate Oral Option. Dependancy can take place at advisable dosages and In the event the drug is misused or abused. Pitfalls are enhanced in individuals with a private or family record of substance abuse (like drug or alcohol abuse or habit) or mental illness (e.g., key despair).
The phosphate salt of codeine takes place as white, needle-formed crystals or white crystalline powder. Codeine phosphate is freely soluble in h2o and somewhat soluble in Alcoholic beverages.
Bluish lips or skin chills clay-colored stools chilly sweats confusion cough dim urine lessen during the frequency of urination lower inside the urine quantity diarrhea challenging or troubled respiration issues in passing urine (dribbling) dizziness dizziness, faintness, or lightheadedness when obtaining up from lying or sitting down situation rapid, pounding, or irregular heartbeat or pulse emotion of heat fever headache large fever hives or welts, itching, or rash improved sweating irregular, quick or slow, or shallow respiratory significant, hive-like swelling around the experience, eyelids, lips, tongue, throat, hands, legs, ft, or sex organs lack of appetite lack of bladder Management nausea noisy respiration not respiration distressing urination pale or blue lips, fingernails, or skin rectal bleeding redness in the facial area, neck, arms, and infrequently, upper chest redness of the skin looking at, hearing, or experience points that are not there seizures serious muscle stiffness shakiness while in the legs, arms, or fingers abdomen pain perspiring tightness from the upper body tiredness trembling or shaking from the fingers or ft uncomfortable breath odor unusual tiredness or weak spot unusually pale pores and skin vomiting of blood yellow eyes or skin Get crisis support straight away if any of the next signs and symptoms of overdose take place:
Drug interactions may perhaps modify how your prescription drugs operate or boost your threat for serious Negative effects. This doc will not contain all probable drug interactions.
This is very important for elderly sufferers, who might be a lot more delicate to the effects of pain medicines. If an excessive amount of the medicine is taken for a long period, it could grow to be habit-forming (triggering psychological or Actual physical dependence) or result in an overdose.
Codeine is Promethazine codeine syrup documented to point out no proof of carcinogenicity or mutagenicity in many different exam methods, such as the micronucleus and sperm abnormality assays and the Salmonella assay. Promethazine was nonmutagenic within the Salmonella check method of Ames.
Small hypertension. A sudden drop in blood pressure level can transpire in some individuals all through treatment with Promethazine Hydrochloride and Codeine Phosphate Oral Answer which may well lead to you to come to feel dizzy, faint, lightheaded, or weak, especially when you rise up (orthostatic hypotension). Your threat of getting this problem might be elevated if you are taking Promethazine Hydrochloride and Codeine Phosphate Oral Solution with specified other medicines that reduce hypertension.
The effect of promethazine and/or codeine about the later expansion and enhancement in the newborn is mysterious.